Physician Assistant salary in South Carolina
What physician assistants earn in South Carolina and its metro areas, compared with the rest of the country.
Median pay$122,490$58.89 per hour
vs U.S.−10%U.S. median $135,880
Middle half earn$105,560 – $134,100Top 10%: $158,860+
Jobs2,2500.94× the U.S. concentration
Physician Assistant pay in South Carolina cities
Metro areas as BLS defines them. Click a column to sort.
| Metro area | Median | Hourly | Jobs |
|---|---|---|---|
| Charlotte-Concord-Gastonia, NC-SC | $133,140 | $64.01 | 1,680 |
| Charleston-North Charleston, SC | $128,920 | $61.98 | 620 |
| Greenville-Anderson-Greer, SC | $123,310 | $59.28 | 440 |
| Columbia, SC | $115,840 | $55.69 | 400 |
| Augusta-Richmond County, GA-SC | $117,240 | $56.37 | 350 |
| Myrtle Beach-Conway-North Myrtle Beach, SC | $125,700 | $60.43 | 140 |
| Northwestern South Carolina nonmetropolitan area | $122,690 | $58.99 | 110 |
| Florence, SC | $120,290 | $57.83 | 90 |
| Hilton Head Island-Bluffton-Port Royal, SC | $125,350 | $60.26 | 80 |
| Spartanburg, SC | $121,990 | $58.65 | 80 |
| Northeastern South Carolina nonmetropolitan area | $116,060 | $55.80 | 70 |
| Southern South Carolina nonmetropolitan area | $156,000 | $75.00 | 40 |
Hospitals and jobs in South Carolina
Physician Assistant pay in similar states
West Virginia · $128,610 Pennsylvania · $127,070 Kansas · $125,640 Kentucky · $120,760 Arkansas · $118,430 Tennessee · $118,240
Other healthcare salaries in South Carolina
Registered Nurses · $82,360 Home Health and Personal Care Aides · $30,110 Nursing Assistants · $37,220 Medical Assistants · $41,160 Licensed Practical and Licensed Vocational Nurses · $61,820 Pharmacy Technicians · $42,120 Nurse Practitioners · $123,290 Dental Assistants · $47,320 Pharmacists · $135,700 Physicians, All Other · $274,480 Clinical Laboratory Technologists and Technicians · $55,280 Emergency Medical Technicians · $40,370
Questions
How much does a physician assistant make in South Carolina?
Physician Assistants in South Carolina earned a median of $122,490 a year ($58.89 an hour) in May 2025, 10% less than the national median of $135,880. The middle half earned $105,560 to $134,100.
Where in South Carolina do physician assistants earn the most?
Among areas in South Carolina, pay was highest in Charlotte-Concord-Gastonia, NC-SC at $133,140.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, all industries. Pay doesn't reflect cost of living, overtime or shift differentials.