Registered Nurse salary in South Carolina
What registered nurses earn in South Carolina and its metro areas, compared with the rest of the country.
Median pay$82,360$39.60 per hour
vs U.S.−16%U.S. median $97,550
Middle half earn$77,320 – $97,230Top 10%: $106,520+
Jobs49,7500.99× the U.S. concentration
Registered Nurse pay in South Carolina cities
Metro areas as BLS defines them. Click a column to sort.
| Metro area | Median | Hourly | Jobs |
|---|---|---|---|
| Charlotte-Concord-Gastonia, NC-SC | $90,620 | $43.57 | 27,010 |
| Charleston-North Charleston, SC | $92,800 | $44.62 | 9,760 |
| Greenville-Anderson-Greer, SC | $81,400 | $39.14 | 9,730 |
| Columbia, SC | $81,920 | $39.39 | 9,400 |
| Augusta-Richmond County, GA-SC | $87,760 | $42.19 | 6,880 |
| Spartanburg, SC | $82,360 | $39.60 | 4,440 |
| Myrtle Beach-Conway-North Myrtle Beach, SC | $80,640 | $38.77 | 3,150 |
| Florence, SC | $81,170 | $39.02 | 3,120 |
| Northwestern South Carolina nonmetropolitan area | $82,620 | $39.72 | 1,810 |
| Hilton Head Island-Bluffton-Port Royal, SC | $81,400 | $39.14 | 1,410 |
| Southern South Carolina nonmetropolitan area | $81,800 | $39.33 | 1,100 |
| Northeastern South Carolina nonmetropolitan area | $79,500 | $38.22 | 1,060 |
| Sumter, SC | $86,260 | $41.47 | 670 |
Hospitals and jobs in South Carolina
Registered Nurse pay in similar states
Indiana · $83,500 Oklahoma · $82,920 Ohio · $82,510 Missouri · $81,780 Tennessee · $81,500 Kentucky · $81,040
Other healthcare salaries in South Carolina
Home Health and Personal Care Aides · $30,110 Nursing Assistants · $37,220 Medical Assistants · $41,160 Licensed Practical and Licensed Vocational Nurses · $61,820 Pharmacy Technicians · $42,120 Nurse Practitioners · $123,290 Dental Assistants · $47,320 Pharmacists · $135,700 Physicians, All Other · $274,480 Clinical Laboratory Technologists and Technicians · $55,280 Emergency Medical Technicians · $40,370 Physical Therapists · $101,330
Questions
How much does a registered nurse make in South Carolina?
Registered Nurses in South Carolina earned a median of $82,360 a year ($39.60 an hour) in May 2025, 16% less than the national median of $97,550. The middle half earned $77,320 to $97,230.
Where in South Carolina do registered nurses earn the most?
Among areas in South Carolina, pay was highest in Charleston-North Charleston, SC at $92,800.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, all industries. Pay doesn't reflect cost of living, overtime or shift differentials.