Registered Nurse salary in Missouri
What registered nurses earn in Missouri and its metro areas, compared with the rest of the country.
Median pay$81,780$39.32 per hour
vs U.S.−16%U.S. median $97,550
Middle half earn$76,050 – $98,560Top 10%: $104,390+
Jobs76,3101.20× the U.S. concentration
Registered Nurse pay in Missouri cities
Metro areas as BLS defines them. Click a column to sort.
| Metro area | Median | Hourly | Jobs |
|---|---|---|---|
| St. Louis, MO-IL | $83,180 | $39.99 | 35,200 |
| Kansas City, MO-KS | $83,040 | $39.92 | 29,650 |
| Springfield, MO | $79,370 | $38.16 | 6,820 |
| Columbia, MO | $84,330 | $40.54 | 3,680 |
| Southeast Missouri nonmetropolitan area | $77,220 | $37.12 | 3,650 |
| Central Missouri nonmetropolitan area | $78,810 | $37.89 | 2,800 |
| Joplin, MO-KS | $74,930 | $36.03 | 2,670 |
| North Missouri nonmetropolitan area | $78,230 | $37.61 | 2,020 |
| Jefferson City, MO | $85,010 | $40.87 | 1,910 |
| St. Joseph, MO-KS | $77,240 | $37.13 | 1,490 |
| Cape Girardeau, MO-IL | $82,640 | $39.73 | 1,470 |
| Southwest Missouri nonmetropolitan area | $79,660 | $38.30 | 1,270 |
Hospitals and jobs in Missouri
Registered Nurse pay in similar states
Oklahoma · $82,920 Ohio · $82,510 South Carolina · $82,360 Tennessee · $81,500 Kentucky · $81,040 North Dakota · $80,730
Other healthcare salaries in Missouri
Home Health and Personal Care Aides · $33,080 Nursing Assistants · $37,680 Licensed Practical and Licensed Vocational Nurses · $61,530 Medical Assistants · $40,440 Pharmacy Technicians · $40,100 Nurse Practitioners · $129,930 Clinical Laboratory Technologists and Technicians · $60,300 Dental Assistants · $45,970 Pharmacists · $137,610 Health Technologists and Technicians, All Other · $46,040 Radiologic Technologists and Technicians · $73,080 Physical Therapists · $99,310
Questions
How much does a registered nurse make in Missouri?
Registered Nurses in Missouri earned a median of $81,780 a year ($39.32 an hour) in May 2025, 16% less than the national median of $97,550. The middle half earned $76,050 to $98,560.
Where in Missouri do registered nurses earn the most?
Among areas in Missouri, pay was highest in Jefferson City, MO at $85,010.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2025, all industries. Pay doesn't reflect cost of living, overtime or shift differentials.